Mechanical Abnormalities of the Airway Wall in Adult Mice After Intrauterine Growth Restriction
Developmental abnormalities of airways may impact susceptibility to asthma in later life.We used a maternal hypoxia-induced mouse model of intrauterine growth restriction (IUGR) to examine changes in mechanical properties of the airway wall.Pregnant BALB/c mice were housed under hypoxic conditions (10.5% O2) from gestational day (GD) 11 to GD 17.5